Diabetes is the most prevalent chronic disease at present. It is estimated that approximately 250 million people worldwide have diabetes, representing 5.9% of the adult population. According to a study published recently in Spain, the prevalence of type 2 diabetes varies between 10 and 15%. Cardiovascular complications associated with the disease produce a high social and health costs significantly reducing the quality of life of patients and their families and are the leading cause of death in developed countries. Complications of diabetes with higher economic costs are the "diabetic foot", which consume about 20% of resources devoted to the care of these patients. Each year more than 1 million people worldwide suffer from a leg amputation due to this condition. Between 50% and 70% of non-traumatic amputations occur in patients with diabetes. Most of these amputations are preceded by a foot ulcer. The most important factors related to the development of these ulcers are loss of sensation due to neuropathy, minor trauma, foot deformity and peripheral vascular disease. According to the International Diabetes Federation, 15% of people with diabetes will develop foot ulcers during their lifetime. Interventions aimed at preventing foot ulcers in patients such as the comprehensive control, education of people with diabetes and their families as well as health professionals, have been shown to reduce lower extremity amputations by 50% and 85%.