GENOME MANIPULATION THROUGH SITE-SPECIFIC RECOMBINATION

被引：47

作者：

OW, DW ^{[1
]}

MEDBERRY, SL ^{[1
]}

机构：

[1] UNIV CALIF BERKELEY, DEPT PLANT PATHOL, BERKELEY, CA 94720 USA

来源：

CRITICAL REVIEWS IN PLANT SCIENCES | 1995年 / 14卷 / 03期

关键词：

GENE EXPRESSION; GENE TRANSFER; GENE TARGETING; GENETIC ENGINEERING; CHROMOSOME ENGINEERING; TRANSLOCATION; DELETION; INVERSION;

D O I：

10.1080/713608117

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Several DNA site-specific recombination systems have been shown to function in higher eukaryotic cells. These two-component systems consist of a single-polypeptide recombinase and a short recognition sequence of less than 35 bp. Strategic placement of the recognition sites into the plant genome has permitted the deletion, inversion, integration, and translocation of host and introduced DNA fragments. Recombinase-based strategies afford precise and predictable engineering of the plant genome.

引用

页码：239 / 261

页数：23

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