EFFECT OF HYDROGEN-FLUORIDE INHALATION ON LIPID-METABOLISM IN GUINEA-PIGS

被引：0
|
作者：
PHILIBERT, C [1 ]
DOUSSET, JC [1 ]
RIOUFOL, C [1 ]
BOURBON, P [1 ]
机构：
[1] FAC PHARM TOULOUSE,DEPT TOXICOL,F-31400 TOULOUSE,FRANCE
来源：
ARTERY | 1991年 / 18卷 / 05期
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D O I：
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中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The action of fluoride in vivo (exposure 96 hrs to 7 mg/m3) on the metabolism of cyclic AMP and relationship between cAMP and lipid metabolism was investigated. The mean values for cAMP, non esterified fatty acids and cholesterol were significantly increased after hydrogen fluoride exposure. cAMP is directly responsible for the increased lipolysis. In animals exposed to HF, theophylline injection causes increases of non esterified fatty acids and not produces modification of cholesterol level.
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页码：226 / 234
页数：9
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