INFLUENCE OF CA2+ ON SYNAPTIC MORPHOLOGY OF FISH CONE PHOTORECEPTORS

被引：10
|
作者：
SCHMITZ, F
DRENCKHAHN, D
机构：
[1] Institute of Anatomy, Julius-Maximilians-University, Würzburg
来源：
BRAIN RESEARCH | 1991年 / 546卷 / 02期
关键词：
PHOTORECEPTOR; CONE; SYNAPSE; EXOCYTOSIS; CA2+;
D O I：
10.1016/0006-8993(91)91499-Q
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Isolated fish retinas were incubated with the Ca2+-ionophore A23187 at various Ca2+ concentrations. Computer reconstructions of the ultrastructure of cone synapses revealed pronounced reduction of the presynaptic surface (complete loss of the synaptic invaginations) in response to low intracellular Ca2+ (< 10(-8) M). No obvious effect on synaptic morphology was noticed at Ca2+ greater than 10(-8) M. Ca2+-dependent exocytotic activity appears to be a major factor controlling the invaginated morphology of cone synapses.
引用
收藏
页码：341 / 344
页数：4
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