SYNTHESIS AND REACTIVITY OF 3-OXAZOLINES

被引：0
|
作者：
WEBER, M [1 ]
JAKOB, J [1 ]
MARTENS, J [1 ]
机构：
[1] UNIV OLDENBURG,FACHBEREICH CHEM,AMMERLANDER HEERSTR 114-118,W-2900 OLDENBURG,GERMANY
来源：
LIEBIGS ANNALEN DER CHEMIE | 1992年 / 01期
关键词：
OXAZOLE, 2,5-DIHYDRO-; OXAZOLIDINE; ACYLIMINIUM ION;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
3-Oxazolines 1 have been prepared from alpha-hydroxy aldehydes, ammonia, water and a second oxo compound (aldehyde or ketone) in a one-pot reaction. Carboxylic acid chlorides add to the azomethine bond of 1 to yield 3-acyl-4-chlorooxazolidines 2, 4-Hydroxy and 4-alkoxyoxazolidines 3 are obtained from 2 upon treatment with aqueons sodium hydroxide or alkanol/triethyl amine, respectively. Some oxazolidines 3 are formed with high diastereoseselectivity.
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页码：1 / 6
页数：6
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