PHOTOCHEMOTHERAPY OF HYPERVASCULAR DERMAL LESIONS - A POSSIBLE ALTERNATIVE TO PHOTOTHERMAL THERAPY

被引：48
|
作者：
ORENSTEIN, A [1 ]
NELSON, JS [1 ]
LIAW, LHL [1 ]
KAPLAN, R [1 ]
KIMEL, S [1 ]
BERNS, MW [1 ]
机构：
[1] UNIV CALIF IRVINE,BECKMAN LASER INST & MED CLIN,1002 HLTH SCI RD E,IRVINE,CA 92715
来源：
LASERS IN SURGERY AND MEDICINE | 1990年 / 10卷 / 04期
关键词：
chicken combs; laser; photodynamic therapy; port wine stain; vascular skin lesions;
D O I：
10.1002/lsm.1900100406
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
Continued improvement in the results of laser treatment of port wine stain, with reduction in scarring, will depend on the ability to use lasers to induce selective injury of only the abnormal blood vessels in the dermis while sparing the normal overlying epidermis. Photodynamic therapy, using an exogenous photosensitizing drug specifically activated by certain wavelengths of light, may be used to destroy selectively certain targets in biological systems. The current study demonstrates, in the chicken comb model, that photochemotherapy can be used to treat hypervascular dermal lesions while leaving the normal overlying epidermis completely intact. Copyright © 1990 Wiley‐Liss, Inc., A Wiley Company
引用
收藏
页码：334 / 343
页数：10
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