Only 22.7 % of pregnant women are immunized against the flu virus, by the popular belief that the vaccine can cause the onset of the disease or other complications. OBJECTIVE. To review the scientific evidence regarding the safety and efficacy of influenza vaccines in pregnant women. METHODOLOGY. Literature review of the scientific literature. RESULTS. Pregnant women and the fetus can have complications if they contract the flu. The influenza vaccine in pregnant women is effective in reducing flu boxes during pregnancy, and it is not observed any increase in adverse effects of the vaccine in mothers or children, compared with non pregnant women. CONCLUSIONS. Vaccination is safe for pregnant women and fetus and is well tolerated. Therefore, vaccination is the safest and most effective method to prevent infection in any trimester.
机构:
Univ Med Ctr Rotterdam, Erasmus MC, Dept Gen Practice, NL-3000 DR Rotterdam, NetherlandsUniv Med Ctr Rotterdam, Erasmus MC, Dept Gen Practice, NL-3000 DR Rotterdam, Netherlands
van der Wouden, JC
Bueving, HJ
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Univ Med Ctr Rotterdam, Erasmus MC, Dept Gen Practice, NL-3000 DR Rotterdam, NetherlandsUniv Med Ctr Rotterdam, Erasmus MC, Dept Gen Practice, NL-3000 DR Rotterdam, Netherlands
机构:
Sanofi Pasteur, Global Pharmacovigilance & Pharmacoepidemiol, Toronto, ON, CanadaSanofi Pasteur, Global Pharmacovigilance & Pharmacoepidemiol, Toronto, ON, Canada
Khromava, Alena
Cohen, Christopher J.
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GlaxoSmithKline Biol, Biol Clin Safety & Pharmacovigilance, King Of Prussia, PA USASanofi Pasteur, Global Pharmacovigilance & Pharmacoepidemiol, Toronto, ON, Canada
Cohen, Christopher J.
Mazur, Marie
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CSL Biotherapies, WorldWide Commercial Operat, King Of Prussia, PA USASanofi Pasteur, Global Pharmacovigilance & Pharmacoepidemiol, Toronto, ON, Canada
Mazur, Marie
Kanesa-thasan, Niranjan
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Novartis Vaccines & Diagnost Inc, External Collaborat & Special Projects, Cambridge, MA USASanofi Pasteur, Global Pharmacovigilance & Pharmacoepidemiol, Toronto, ON, Canada
Kanesa-thasan, Niranjan
Crucitti, Antonio
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Novartis Vaccines & Diagnost, Pharmacovigilance Dept, Siena, ItalySanofi Pasteur, Global Pharmacovigilance & Pharmacoepidemiol, Toronto, ON, Canada
Crucitti, Antonio
Seifert, Harry
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GlaxoSmithKline Biol, Biol Clin Safety & Pharmacovigilance, King Of Prussia, PA USASanofi Pasteur, Global Pharmacovigilance & Pharmacoepidemiol, Toronto, ON, Canada