Hydroxyurea;
pneumopathy;
drug complications;
myeloproliferative syndrome;
desquamative pneumonia;
drug-induced pneumopathy;
D O I:
10.1177/1179547618770688
中图分类号:
R5 [内科学];
学科分类号:
1002 ;
100201 ;
摘要:
Hydroxyurea (HU) is a drug frequently used in the treatment of chronic myeloproliferative neoplasms. The most common side effects of this drug are pancytopenia, digestive and skin disorders. Respiratory complications are rare and there are less than 20 cases described, only 5 of which underwent an anatomopathological study. We present the case of a patient with chronic myeloproliferative neoplasm who developed interstitial pneumonitis probably due to HU according to histological study.
机构:
Univ Milan, Hematol & Transplantat Unit, Fdn IRCCS Ca Granda Osped Maggiore Policlin, Milan, ItalyUniv Milan, Hematol & Transplantat Unit, Fdn IRCCS Ca Granda Osped Maggiore Policlin, Milan, Italy
Freyrie, A.
Guidotti, F.
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机构:
Univ Milan, Hematol & Transplantat Unit, Fdn IRCCS Ca Granda Osped Maggiore Policlin, Milan, ItalyUniv Milan, Hematol & Transplantat Unit, Fdn IRCCS Ca Granda Osped Maggiore Policlin, Milan, Italy
Guidotti, F.
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Ferla, V.
Fracchiolla, N. S.
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机构:
Univ Milan, Hematol & Transplantat Unit, Fdn IRCCS Ca Granda Osped Maggiore Policlin, Milan, ItalyUniv Milan, Hematol & Transplantat Unit, Fdn IRCCS Ca Granda Osped Maggiore Policlin, Milan, Italy
Fracchiolla, N. S.
Tarsia, P.
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机构:
Univ Milan, Resp Med Sect, Fdn IRCCS Ca Granda Osped Maggiore Policlin, Milan, ItalyUniv Milan, Hematol & Transplantat Unit, Fdn IRCCS Ca Granda Osped Maggiore Policlin, Milan, Italy