Left Ventricular Systolic Dysfunction in Patients with Chronic Kidney Disease

Cardiovascular disease including left ventricular systolic dysfunction is a common complication in patients with chronic kidney disease. However, frequency of left ventricular systolic dysfunction in patients with chronic kidney disease in local population is not known. All patients with chronic kidney disease between ages of 20-80 years who were not yet on hemodialysis or peritoneal dialysis and who were admitted to a tertiary care facility over a 6 month period were included in the study. Left ventricular systolic dysfunction was assessed by 2 D echocardiography. A total of 110 patients were included in the study. Mean age of patients was 50.4 +/- 14.2 years. Of all patients, 65(59.1%) were males and 45(40.9%) were females, 94(87%) had hypertension and 74(69.8%) had diabetes mellitus. Mean serum creatinine and mean eGFR were 7.3 +/- 3.5 mg/dl and 10.6 +/- 9.3 ml/min/1.73 m(2) respectively. Mean ejection fraction was 54.5 +/- 12.9%. Left ventricular systolic dysfunction (EF<55%) was found in 35 (32.4%) patients. Our study showed that a third of patients with chronic kidney disease had left ventricular systolic dysfunction.