N-(5-INDANYLSULFONYL)-N'-(4-CHLOROPHENYL)UREA, A NOVEL AGENT EQUALLY CYTOTOXIC TO NONPROLIFERATING HUMAN-COLON ADENOCARCINOMA CELLS

被引：0

作者：

HOUGHTON, PJ ^{[1
]}

BAILEY, FC ^{[1
]}

GERMAIN, GS ^{[1
]}

GRINDEY, GB ^{[1
]}

WITT, BC ^{[1
]}

HOUGHTON, JA ^{[1
]}

机构：

[1] ELI LILLY INT CORP, INDIANAPOLIS, IN 46285 USA

来源：

CANCER RESEARCH | 1990年 / 50卷 / 02期

关键词：

D O I：

暂无

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

引用

页码：318 / 322

页数：5

共 28 条

[1] EVALUATION OF N-(5-INDANYLSULFONYL)-N'-(4-CHLOROPHENYL)-UREA AGAINST XENOGRAFTS OF PEDIATRIC RHABDOMYOSARCOMA
HOUGHTON, PJ
HOUGHTON, JA
MYERS, L
CHESHIRE, P
HOWBERT, JJ
GRINDEY, GB
CANCER CHEMOTHERAPY AND PHARMACOLOGY, 1989, 25 (02) : 84 - 88
[2] DIARYLSULFONYLUREAS AND RADIOTHERAPY .1. INVITRO STUDIES WITH N-(5-INDANYLSULFONYL)-N'-(4-CHLOROPHENYL)-UREA (SULOFENUR)
ROCKWELL, S
GRINDEY, GB
CANCER COMMUNICATIONS, 1991, 3 (04): : 103 - 108
[3] EVIDENCE FOR MITOCHONDRIAL LOCALIZATION OF N-(4-METHYLPHENYLSULFONYL)-N'-(4-CHLOROPHENYL)UREA IN HUMAN COLON ADENOCARCINOMA CELLS
HOUGHTON, PJ
BAILEY, FC
HOUGHTON, JA
MURTI, KG
HOWBERT, JJ
GRINDEY, GB
CANCER RESEARCH, 1990, 50 (03) : 664 - 668
[4] CROSS-RESISTANCE TO ANTITUMOR DIARYLSULFONYLUREAS AND COLLATERAL SENSITIVITY TO MITOCHONDRIAL TOXINS IN A HUMAN CELL-LINE SELECTED FOR RESISTANCE TO THE ANTITUMOR AGENT N-(5-INDANYLSULFONYL)N'-(4-CHLOROPHENYL)UREA
SOSINSKI, J
THAKAR, JH
GERMAIN, GS
DIAS, P
HARWOOD, FC
KUTTESCH, JF
HOUGHTON, PJ
MOLECULAR PHARMACOLOGY, 1994, 45 (05) : 962 - 970
[5] CHARACTERIZATION OF THE INTRACELLULAR-DISTRIBUTION AND BINDING IN HUMAN ADENOCARCINOMA CELLS OF N-(4-AZIDOPHENYLSULFONYL)-N'-(4-CHLOROPHENYL)UREA (LY219703), A PHOTOAFFINITY ANALOG OF THE ANTITUMOR DIARYLSULFONYLUREA SULOFENUR
HOUGHTON, PJ
SOSINSKI, J
THAKAR, JH
BODER, GB
GRINDEY, GB
BIOCHEMICAL PHARMACOLOGY, 1995, 49 (05) : 661 - 668
[6] INFLUENCE OF EXTRACELLULAR PH ON THE ACCUMULATION AND CYTOTOXICITY OF N-(4-METHYLPHENYLSULFONYL)-N'-(4-CHLOROPHENYL)UREA IN HUMAN CELL-LINES
SOSINSKI, J
CHAPIN, C
THAKAR, JH
HOUGHTON, PJ
CANCER COMMUNICATIONS, 1991, 3 (12): : 373 - 381
[7] SYNTHESIS OF N-(1-KETO-) AND N-(1-HYDROXY-5-INDANSULFONYL)-N'-(4-CHLOROPHENYL)UREA, 2 MAJOR METABOLITES OF THE ANTITUMOR AGENT SULOFENUR (LY186641)
HOWBERT, JJ
CROWELL, TA
SYNTHETIC COMMUNICATIONS, 1990, 20 (20) : 3193 - 3200
[8] N-(4-CHLOROPHENYL)-N-HYDROXY-N'-(3-CHLOROPHENYL)UREA, A GENERAL REDUCING AGENT FOR 5-LIPOXYGENASES, 12-LIPOXYGENASES, AND 15-LIPOXYGENASES AND A SUBSTRATE FOR THEIR PSEUDOPEROXIDASE ACTIVITIES
FALGUEYRET, JP
DESMARAIS, S
ROY, PJ
RIENDEAU, D
BIOCHEMISTRY AND CELL BIOLOGY-BIOCHIMIE ET BIOLOGIE CELLULAIRE, 1992, 70 (3-4): : 228 - 236
[9] MECHANISM OF KILLING OF HELA-CELLS BY THE ANTITUMOR SULFONYLUREA, N-(4-METHYLPHENYLSULFONYL)-N'-(4-CHLOROPHENYL)UREA (LY-181984)
MORRE, DM
MORRE, DJ
PROTOPLASMA, 1995, 184 (1-4) : 188 - 195
[10] RESPONSE OF NADH OXIDATION AND GROWTH IN K-562 CELLS TO THE ANTITUMOR SULFONYLUREA, N-(4-METHYLPHENYLSULFONYL)-N'-(4-CHLOROPHENYL)UREA (LY181984)
MOYACAMARENA, SY
MORRE, DJ
MORRE, DM
PROTOPLASMA, 1995, 188 (3-4) : 151 - 160

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