CYCLIC REMODELING OF GROWTH CONE LAMELLAE AND THE EFFECT OF TARGET TISSUE

被引:7
|
作者
GALLO, G
POLLACK, ED
机构
[1] UNIV ILLINOIS,DEPT BIOL SCI,CHICAGO,IL 60608
[2] UNIV ILLINOIS,COMM NEUROSCI,CHICAGO,IL 60608
来源
DEVELOPMENTAL BRAIN RESEARCH | 1995年 / 85卷 / 01期
关键词
GROWTH CONE; LAMELLA; CYCLIC REMODELING; TARGET TISSUE; AXON GUIDANCE; MOTILITY;
D O I
10.1016/0165-3806(94)00201-A
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
We report the existence of cyclical fluctuations in the total size of growth cone lamellae, represented by membrane protrusions and retractions, and show that aspects of this behavior can be regulated by the target tissue for the nerve fibers. The transition of the growth cone from a high to a less motile state, which occurs in the presence of the target tissue, has implications for the mechanisms that underlie nerve fiber elongation during development.
引用
收藏
页码:140 / 145
页数:6
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