THE ROLE OF MYOINOSITOL IN THE PATHOGENESIS OF DIABETIC COMPLICATIONS

被引：8
|
作者：
BAXTER, MA
机构：
[1] University of Birmingham
来源：
TRENDS IN ENDOCRINOLOGY AND METABOLISM | 1991年 / 2卷 / 05期
关键词：
D O I：
10.1016/1043-2760(91)90017-H
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
It is tempting to speculate that all diabetic complications are generated by a single biochemical abnormality. The observation that intracellular inositol depletion occurs in diabetes mellitus has led to the hypothesis that this may be of importance in the pathogenesis of diabetic complications. The central role of inositol and inositol derivatives in cellular function has given support to this theory, but as yet no fully substantiated mechanistic model can be offered.
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页码：187 / 190
页数：4
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