Invasive aspergillosis following the heart transplantation - A case report

According to the ISHLT registry infectious complications are the leading cause of death in the first year after heart transplantation. Presented case report describes the fate of 63-year-old patient with heart failure due to coronary artery heart disease, which in March 2012, underwent a heart transplantation. In May comes with symptoms of respiratory infection. Diagnosed invasive aspergillus pneumonia, for which deployed specific treatment with voriconazole. For unsatisfactory effect enhanced by the addition of amphotericin B. Despite all the care patient a month after diagnosis dies of sepsis. A subsequent autopsy found the cause of death: abscessing necrotizing bronchopneumonia, but the surprise was the absence of fungal elements both by microscopy and cultivation. (C) 2016 Published by Elsevier Sp. zo.o. on behalf of the Czech Society of Cardiology.