ELECTROCHEMICAL DETERMINATION OF ALLOPURINOL BASED ON ITS INTERACTION WITH XANTHINE-OXIDASE

被引：22
|
作者：
MARTIN, GB [1 ]
RECHNITZ, GA [1 ]
机构：
[1] UNIV HAWAII MANOA,DEPT CHEM,HAWAII BIOSENSOR LAB,HONOLULU,HI 96822
来源：
ANALYTICA CHIMICA ACTA | 1990年 / 237卷 / 01期
基金：
美国国家科学基金会;
关键词：
Allopurinol; Biosensor; Enzyme electrode;
D O I：
10.1016/S0003-2670(00)83905-7
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
Allopurinol was determined in the range 0.20-50 μM utilizing xanthine oxidase immobilized onto a carbon paste electrode. Alternative assay methods relying on either inhibition of enzymatic activity or direct formation of a product are evaluated. Regeneration of xanthine oxidase activity under various conditions is also surveyed. © 1990.
引用
收藏
页码：91 / 98
页数：8
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