REGIOSELECTIVE N-ALKYLATION IN 5-FLUOROURACIL

被引：17
|
作者：
GACEK, M
UNDHEIM, K
机构：
来源：
ACTA CHEMICA SCANDINAVICA SERIES B-ORGANIC CHEMISTRY AND BIOCHEMISTRY | 1979年 / 33卷 / 07期
关键词：
D O I：
10.3891/acta.chem.scand.33b-0515
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
5-Fluorouracil [an antineoplastic drug] was alkylated selectively on N-1 via its 4-methylthio derivative. Similarly N-3 alkylation was achieved via the 2-methylthio derivative of 5-fluorouracil.
引用
收藏
页码：515 / 518
页数：4
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