CARDIAC TRANSPLANTATION IN PATIENTS OLDER THAN 55 YEARS

被引:0
|
作者
DEFRAIGNE, JO [1 ]
DEMOULIN, JC [1 ]
VANDAMME, H [1 ]
DELBOUILLE, MH [1 ]
MEURISSE, M [1 ]
LIMET, R [1 ]
机构
[1] CHU LIEGE,DEPT CARIOVASC & THORAC SURG,B-35,B-4000 LIEGE 1,BELGIUM
关键词
HEART DISEASES; HEART FAILURE; HEART SURGERY; HEART; TRANSPLANTATION; AGING; PROGNOSIS;
D O I
暂无
中图分类号
R61 [外科手术学];
学科分类号
摘要
From 1985 to 1990, 27 patients older than 55 years (extremes 55-65 years; 21 men and 6 women) received a cardiac transplant. The cause of cardiopathy was ischemic in 70%. Postoperative immunosuppressive therapy consisted of Cyclosporin A, steroids, azathioprine and antilymphocytic serum. Rejection episodes were monitored by endomyocardial biopsies and treated by pulses of steroids or monoclonal antibodies (OKT3). The operative mortality is 7,4% (n = 2). The one and two year survivals are 71% and 62% respectively. Ther incidence of infection and/or rejection were 0,71 +/- 0,4 and 1,4 +/- 0,7 episodes/patient/year. Age beyond 55 years does not contraindicate heart transplantation. This change in recipient selection policy should lead to parallel changes in donor selection criteria.
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页码:38 / 42
页数:5
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