(-)DEPRENYL (SELEGILINE) IS DEVOID OF AMPHETAMINE-LIKE BEHAVIORAL-EFFECTS IN RATS

被引：0
|
作者：
TIMAR, J
KNOLL, B
KNOLL, J
机构：
来源：
ACTA PHYSIOLOGICA HUNGARICA | 1992年 / 79卷 / 02期
关键词：
DEPRENYL; AMPHETAMINE; BEHAVIORAL EFFECTS;
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学科分类号：
摘要：
Central effects of high dose (-)deprenyl (50-100 mg/kg sc) was compared to that of (+)deprenyl and (+/-)amphetamine (AM). (+)Deprenyl and AM induced stereotyped behaviour, increased spontaneous motility in smaller and decreased it in higher doses, inhibited escape behaviour and shutle-box avoidance. (-)Deprenyl failed to possess any of these effects, providing further evidence that AM-type metabolites have no share in the action of (-)deprenyl.
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页码：131 / 137
页数：7
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