THE PARASYMPATHETIC NERVOUS-SYSTEM AND THE DIURNAL-VARIATION OF LUNG-MECHANICS IN ASTHMA

被引：27
|
作者：
MORRISON, JFJ [1 ]
PEARSON, SB [1 ]
机构：
[1] KILLINGBECK HOSP,PULM FUNCT LAB,LEEDS LS14 6UQ,ENGLAND
来源：
RESPIRATORY MEDICINE | 1991年 / 85卷 / 04期
关键词：
D O I：
10.1016/S0954-6111(06)80098-3
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
In a placebo-controlled double-blind experiment the effects of cholinergic blockade with 30 μg kg−1 atropine administered by intravenous injection have been studied in nocturnal asthma. Cholinergic blockade at night reversed the changes in indices of airflow in small airways and of gas trapping to the values seen after administration of atropine during the daytime. However, the improvement in indices of airflow in large airways was not complete, reaching only the daytime placebo levels. No changes were seen in any aspect of breathing pattern. The results are discussed in relation to the literature. © 1991, Baillière Tindall All rights reserved. All rights reserved.
引用
收藏
页码：285 / 289
页数：5
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