THE MECHANISMS OF THE OXIDATION OF NADH ANALOGS .2. N-METHYL-SUBSTITUTED 1,4-DIHYDROPYRIDINES

被引：22
|
作者：
KRUPPA, AI
TARABAN, MB
POLYAKOV, NE
LESHINA, TV
LUSIS, V
MUCENIECE, D
DUBURS, G
机构：
[1] NOVOSIBIRSK CHEM KINET & COMBUST INST,NOVOSIBIRSK 630090,RUSSIA
[2] RIGA ORGAN SYNTH INST,RIGA 226006,LATVIA
来源：
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY | 1993年 / 73卷 / 02期
关键词：
D O I：
10.1016/1010-6030(93)80045-B
中图分类号：
O64 [物理化学（理论化学）、化学物理学];
学科分类号：
070304 ; 081704 ;
摘要：
The mechanism of the photoinitiated oxidation of N-methyl-substituted 1,4-dihydropyridines (1,4-DHPs) by quinones was studied in acetonitrile. Electron transfer with the formation of a radical ion pair (radical cation of 1,4-DHP and radical anion of acceptor) forms the initial stage of the process. Abstraction of a hydrogen atom from the 1,4-DHP radical cation in the bulk leads to the formation of the main product of photo-oxidation - pyridinium cation. Traces of water in the reaction mixture and the pH exert a significant influence on the photo-oxidation of N-substituted 1,4-DHPs.
引用
收藏
页码：159 / 163
页数：5
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