REDUCTION OF CSF MONOAMINE METABOLITES IN POSTSTROKE DEPRESSION - A PRELIMINARY-REPORT

被引：0

作者：

BRYER, JB

STARKSTEIN, SE

VOTYPKA, V

PARIKH, RM

PRICE, TR

ROBINSON, RG

机构：

[1] UNIV IOWA,COLL MED,DEPT PSYCHIAT,MED EDUC BLDG,500 NEWTON RD,IOWA CITY,IA 52242

[2] JOHNS HOPKINS UNIV,SCH MED,DEPT PSYCHIAT & BEHAV SCI,BALTIMORE,MD 21205

[3] JOHNS HOPKINS UNIV,SCH MED,DEPT NEUROSCI,BALTIMORE,MD 21205

[4] UNIV MARYLAND,SCH MED,DEPT NEUROL,BALTIMORE,MD 21201

[5] INST NEUROL INVEST DR RAUL CARREA,BUENOS AIRES,ARGENTINA

来源：

JOURNAL OF NEUROPSYCHIATRY AND CLINICAL NEUROSCIENCES | 1992年 / 4卷 / 04期

关键词：

D O I：

暂无

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Monoamine metabolites were measured in the cerebrospinal fluid (CSF) of depressed and nondepressed patients with acute stroke lesions and in nondepressed patients without stroke lesions. Depressed stroke patients had a significantly lower concentration of CSF 5-hydroxyindoleacetic acid (5-HIAA; a serotonin metabolite) than the other two groups. These findings suggest that poststroke depression may be mediated by serotonergic mechanisms.

引用

页码：440 / 442

页数：3

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