COMPLEMENT ACTIVATION IN SYSTEMIC-SCLEROSIS

被引：0
|
作者：
WILD, G
WATKINS, J
WARD, AM
HUGHES, P
HUME, A
ROWELL, NR
机构：
[1] ROYAL HALLAMSHIRE HOSP,DEPT IMMUNOL,SHEFFIELD S10 2JF,S YORKSHIRE,ENGLAND
[2] UNIV SHEFFIELD,NO GEN HOSP,DEPT MED,SHEFFIELD S10 2TN,S YORKSHIRE,ENGLAND
[3] UNIV LEEDS,GEN INFIRM,DEPT DERMATOL,LEEDS LS1 3EX,W YORKSHIRE,ENGLAND
来源：
JOURNAL OF CLINICAL & LABORATORY IMMUNOLOGY | 1990年 / 31卷 / 01期
关键词：
SYSTEMIC SCLEROSIS; COMPLEMENT; ANAPHYLATOXINS; NAFAMSTAT MESILATE;
D O I：
暂无
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
The use of a synthetic protease inhibitor, nafamstat mesilate, has enabled reliable estimations of in vivo complement activation to be made in patients with systemic sclerosis. Elevations of C3a and C4a anaphylatoxins were found in 2 and 24 out of 30 patients respectively, indicating that complement activation, predominantly by the classical pathway, is a common occurrence in the disease, even though complement C3 and C4 levels were within the reference range.
引用
收藏
页码：39 / 41
页数：3
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