Analysis of the clinical symptoms of patients complicated with acute intestinal obstruction after the surgery of colon cancer

Objective: To study the content of serum inflammatory medium of the patients complicated with acute intestinal obstruction after the surgery of colon cancer. Methods: A total of 150 patients with colon cancer received limited surgery treatment during the period of May 2012 to October 2015 were selected as the study objects. They were divided into postoperative ileus (POI) group and non-postoperative ileus (non-POI) group according to the presence or absence of intestinal obstruction. Then, the contents of serum procalcitonin (PCT), C-reactive protein (CRP), tumor necrosis factor-alpha (TNF-alpha) and interleukin-6 (IL-6) were detected at the 1st, 3rd, 5th and 7th days after the surgery. Results: The levels of serum PCT, CRP, TNF-alpha and IL-6 of two groups at the 1st day had no differences after the surgery. The level of serum PCT of POI group tended to increase and its levels of serum CRP, TNF-alpha and IL-6 tended to decrease at the 3rd, 5th and 7th days after the surgery, while the levels of serum PCT, CRP, TNF-alpha and IL-6 of non-POI group were decreased. The content of serum PCT of POI group and non-POI group at the 3rd day after the surgery had no differences (P > 0.05), and the level of serum PCT of POI group was higher than that of non-POI group at the 5th and 7th days after the surgery (P < 0.05). The levels of serum CRP, TNF-alpha and IL-6 of POI group and non-POI group had no differences at the 3rd, 5th and 7th days after the surgery (P > 0.05). Conclusions: The raising of the content of serum PCT after the surgery can be used as the laboratory index to predict the incidence of acute intestinal obstruction after the surgery of colon cancer.