NAPHTHALENE-CATALYZED LITHIATION OF 3-CHLORO-2-CHLOROMETHYLPROPENE - A BARBIER-TYPE PRACTICAL ALTERNATIVE TO THE TRIMETHYLENEMETHANE DIANION

被引：51

作者：

RAMON, DJ ^{[1
]}

YUS, M ^{[1
]}

机构：

[1] UNIV ALICANTE,FAC CIENCIAS,DEPT QUIM ORGAN,APDO 99,E-03080 ALICANTE,SPAIN

来源：

TETRAHEDRON LETTERS | 1992年 / 33卷 / 16期

关键词：

LITHIATION; TRIMETHYLENEMETHANE DIANION; 3-CHLORO-2-CHLOROMETHYLPROPENE; NAPHTHALENE;

D O I：

10.1016/0040-4039(92)88181-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The reaction of equimolar amounts of 3-chloro-2-chloromethylpropene (2) and a carbonyl compound (3) with an excess of lithium powder and a catalytic amount (6%) of naphthalene in tetrahydrofuran at -78-degrees-C leads, after hydrolysis with water, to the corresponding diols 4 in a Barbier-type process.

引用

页码：2217 / 2220

页数：4

共 3 条

[1] NAPHTHALENE-CATALYZED LITHIATION OF 3-CHLORO-2-CHLOROMETHYLPROPENE IN A BARBIER-TYPE PROCESS WITH CARBONYL-COMPOUNDS
GOMEZ, C
RAMON, DJ
YUS, M
TETRAHEDRON, 1993, 49 (19) : 4117 - 4126
[2] 4,4'-DI-TERT-BUTYLBIPHENYL-CATALYZED LITHIATION OF 2,3-DICHLOROPROPENE - A BARBIER-TYPE PRACTICAL ALTERNATIVE TO 2,3-DILITHIOPROPENE
GUIJARRO, A
YUS, M
TETRAHEDRON LETTERS, 1993, 34 (12) : 2011 - 2014
[3] 4,4'-DI-TERT-BUTYLBIPHENYL-CATALYZED LITHIATION OF CHLOROMETHYL ETHYL ETHER - A BARBIER-TYPE NEW AND EASY ALTERNATIVE TO ETHYL LITHIOMETHYL ETHER
GUIJARRO, A
YUS, M
TETRAHEDRON LETTERS, 1993, 34 (21) : 3487 - 3490

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