TISSUE-SPECIFIC AND DEVELOPMENT-SPECIFIC EXPRESSION OF GOAT INSULIN-LIKE GROWTH-FACTOR-I (IGF-I) MESSENGER-RNAS

被引:5
|
作者
MIKAWA, S
YOSHIKAWA, G
YAMANO, Y
SAKAI, H
KOMANO, T
HOSOI, Y
UTSUMI, K
机构
[1] KYOTO UNIV, DEPT AGR CHEM, BIOCHEM LAB, KYOTO 60601, JAPAN
[2] KYOTO UNIV, DEPT ANIM SCI, ANIM REPROD LAB, KYOTO 60601, JAPAN
关键词
D O I
10.1271/bbb.59.759
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
We cloned four kinds of goat insulin-like growth factor-I (IGF-I) cDNAs. Each of them encodes the same mature IGF-T and different signal peptides. In this study, we analyzed expression of the four kinds of mRNAs in tissues in various developmental stages by a reverse transcriptase-polymerase chain reaction assay. The results suggest that their expression may be controlled by different promoters, the activities of which are tissue- and development-specific.
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页码:759 / 761
页数:3
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