TOXICITY OF THE CYSTEINE-S-CONJUGATES AND MERCAPTURIC ACIDS OF 4 STRUCTURALLY RELATED DIFLUOROETHYLENES IN ISOLATED PROXIMAL TUBULAR CELLS FROM RAT-KIDNEY - UPTAKE OF THE CONJUGATES AND ACTIVATION TO TOXIC METABOLITES

被引：50

|

作者：

BOOGAARD, PJ ^{[1
]}

COMMANDEUR, JNM ^{[1
]}

MULDER, GJ ^{[1
]}

VERMEULEN, NPE ^{[1
]}

NAGELKERKE, JF ^{[1
]}

机构：

[1] FREE UNIV AMSTERDAM,DEPT PHARMACOCHEM MOLEC TOXICOL,1081 HV AMSTERDAM,NETHERLANDS

来源：

BIOCHEMICAL PHARMACOLOGY | 1989年 / 38卷 / 21期

关键词：

D O I：

10.1016/0006-2952(89)90579-0

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

收藏

页码：3731 / 3741

页数：11

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[1] UPTAKE OF NEPHROTOXIC S-CONJUGATES BY ISOLATED RAT RENAL PROXIMAL TUBULAR CELLS
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[3] ISOLATED PROXIMAL TUBULAR CELLS FROM RAT-KIDNEY AS AN INVITRO MODEL FOR STUDIES ON NEPHROTOXICITY .1. AN IMPROVED METHOD FOR PREPARATION OF PROXIMAL TUBULAR CELLS AND THEIR FUNCTIONAL-CHARACTERIZATION BY ALPHA-METHYLGLUCOSE UPTAKE
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