ANTIOXIDANT PROPERTIES OF DEHYDROZINGERONE AND CURCUMIN IN RAT-BRAIN HOMOGENATES

被引:64
|
作者
RAJAKUMAR, DV [1 ]
RAO, MNA [1 ]
机构
[1] COLL PHARMACEUT SCI, DEPT PHARMACEUT CHEM, MANIPAL 576119, INDIA
关键词
CURCUMIN; DEHYDROZINGERONE; LIPID PEROXIDATION; CONJUGATED DIENES; ANTIOXIDANTS;
D O I
10.1007/BF00928368
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
The present study investigates the inhibition of lipid peroxidation by dehydrozingerone and curcumin in rat brain homogenates. Both the test compounds inhibited the formation of conjugated dienes and spontaneous lipid peroxidation. These compounds also inhibited lipid peroxidation induced by ferrous ions, ferric-ascorbate and ferric-ADP-ascorbate. In all these cases, curcumin was more active than dehydrozingerone and dl-alpha-tocopherol.
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页码:73 / 79
页数:7
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