STUDIES TOWARD THE TOTAL SYNTHESIS OF (+)-PTILOMYCALIN-A - USE OF A TETHERED BIGINELLI CONDENSATION FOR THE PREPARATION OF AN ADVANCED TRICYCLIC INTERMEDIATE

被引：51

作者：

OVERMAN, LE

RABINOWITZ, MH

机构：

[1] Department of Chemistry, University of California, Irvine

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1993年 / 58卷 / 12期

关键词：

D O I：

10.1021/jo00064a007

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An intramolecular ureidoaldehyde condensation, 16 + (R)-14 --> 19, is the key step in a seven-step preparation of the enantiopure spirotricycle 23, a potential intermediate for the enantioselective total synthesis of ptilomycalin A.

引用

页码：3235 / 3237

页数：3

共 34 条

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