PROTECTIVE EFFICACY OF BCG VACCINE AGAINST LEPROSY IN SOUTHERN MALAWI

被引：15
|
作者：
BAKER, DM
NGUYENVANTAM, JS
SMITH, SJ
机构：
[1] UNIV NOTTINGHAM, QUEENS MED CTR, DEPT PUBL HLTH MED & EPIDEMIOL, NOTTINGHAM NG7 2UH, ENGLAND
[2] UNIV NOTTINGHAM, QUEENS MED CTR, DEPT SURG, NOTTINGHAM NG7 2UH, ENGLAND
来源：
EPIDEMIOLOGY AND INFECTION | 1993年 / 111卷 / 01期
关键词：
D O I：
10.1017/S0950268800056636
中图分类号：
R1 [预防医学、卫生学];
学科分类号：
1004 ; 120402 ;
摘要：
This paper describes a matched case-control study to determine the efficacy of BCG vaccine in preventing the occurrence of leprosy in southern Malawi, a previously unstudied area. The BCG immunization rate amongst 145 individuals with leprosy was 44.8%, compared to 62.5% in 290 matched controls. The protective efficacy of BCG vaccine against leprosy in this region was estimated to be 63.6%; smallpox immunization had no effect. These findings support the view that BCG vaccine should be considered as a control measure in areas where leprosy is endemic.
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页码：21 / 25
页数：5
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