SYNTHESIS OF POLYUREAS BY POLYCONDENSATION OF DIAMINES WITH ACTIVE DERIVATIVES OF CARBONIC-ACID

New polycondensation reactions of active diphenyl carbonates and diphenyl carbamate with diamines were developed for the synthesis of high-molecular-weight polyureas. The kinetics and mechanism of carbonic acid active esters aminolysis model reactions were studied. Possible side reactions including nucleophilic substitution reaction were investigated as well. It is shown that novel methods advantageously distinguish from traditional methods of polyureas synthesis by low tendency to side reactions and facilitate the synthesis of linear polyureas and copolyureas. It is found that N,N'-bis(trimethylsilylated) diamines and salts of diamines as monomers can be successfully used in these reactions. Bioanalogous polymers promising for biomedical application - polyureas based on L-lysine - were synthesized using novel polycondensation reactions.