CYCLIZATION OF POLYENES .49. CYCLIZATION OF EPOXYNEOCEMBRENE DERIVATIVES TO SECOTRINERVITANES

被引：11

作者：

HIRUKAWA, T ^{[1
]}

KOARAI, A ^{[1
]}

KATO, T ^{[1
]}

机构：

[1] SCI UNIV TOKYO,FAC SCI,DEPT CHEM,1-3 KAGURAZAKA,SHINJYUKU KU,TOKYO 162,JAPAN

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1991年 / 56卷 / 14期

关键词：

D O I：

10.1021/jo00014a036

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Four stereoisomers of epoxyneocembrene derivatives 5-8 were treated with BF3.OEt2 as potential model reactions for the proposed biogenesis of secotrinervitane-type diterpenoids (Scheme I). Two of them (5 and 6) afforded secotrinervitane derivatives, while the remaining isomers 7 and 8 gave no cyclization products (Table I). The natural product, secotrinervitene-2-beta,3-alpha-diol (2a) was synthesized from 5 in dl-form.

引用

页码：4520 / 4525

页数：6

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