The correlation of the antral follicle count and Serum anti-mullerian hormone

Objective: To compare the value of the basal serum anti-Mullerian hormone (AMH) level with most of the established ovarian reserve tests. Material and Methods: A total of 141 infertile women was studied prospectively. On cycle day 3, serum levels of AMH, inhibin 13, estradiol (F), FSH and LH levels were measured, and the number of early antral follicles (2-6 mm in diameter) estimated at ultrasound scanning to compare the strengths of hormonal-follicular correlations. Results: The mean age of the participants was 29.18 +/- 5.54. The mean AMU and total AFC on day 3 were 2.23 +/- 1.90 ng/ml and 8.35 +/- 2.83, respectively. Serum AMH levels were more tightly correlated (p<0.001) with number of the early antral follicle count (r=0.467, p<0.0001) than age and serum levels of FSH (r=-0.400, p<0.001; r=-0.299, p<0.001 respectively). No correlation was detected between serum levels of inhibin B, E-2, and LH (r=0.154, p=0.06; p=0.31; r=-0.085 and r=0.067, p=0.42) and AFC. Conclusion: Serum AIM levels showed a strong correlation with AFC, and also this correlation is stronger than the other ovarian reserve parameters.