ROLE OF HYPOXIC PULMONARY VASOCONSTRICTION IN PULMONARY GAS-EXCHANGE AND BLOOD-FLOW DISTRIBUTION .1. PHYSIOLOGICAL CONCEPTS

被引：90
|
作者：
MARSHALL, BE [1 ]
MARSHALL, C [1 ]
FRASCH, F [1 ]
HANSON, CW [1 ]
机构：
[1] UNIV PENN,SCH MED,CTR ANESTHESIA RES,PHILADELPHIA,PA 19104
来源：
INTENSIVE CARE MEDICINE | 1994年 / 20卷 / 04期
关键词：
LUNG; VENTILATION PERFUSION; PRESSURE-FLOW; COMPUTER MODEL;
D O I：
10.1007/BF01708968
中图分类号：
R4 [临床医学];
学科分类号：
1002 ; 100602 ;
摘要：
The regulation of the distribution of ventilation/perfusion ratios by hypoxic pulmonary vasoconstriction contributes to both the efficiency of gas exchange and to pulmonary hemodynamics. In this review, the first of a two part series, are summarized the physiologic principles on which the analysis of ventilation/perfusion ratios and of pressure - flow relationships are based. A new combined analysis is introduced that permits the important contributions of hypoxic pulmonary vasoconstriction to overall gas exchange to be demonstrated in the circumstances of clinical complexity.
引用
收藏
页码：291 / 297
页数：7
相关论文
共 50 条
  • [1] ROLE OF HYPOXIC PULMONARY VASOCONSTRICTION IN PULMONARY GAS-EXCHANGE AND BLOOD-FLOW DISTRIBUTION .2. PATHOPHYSIOLOGY
    MARSHALL, BE
    HANSON, CW
    FRASCH, F
    MARSHALL, C
    [J]. INTENSIVE CARE MEDICINE, 1994, 20 (05) : 379 - 389
  • [2] HYPOXIC PULMONARY VASOCONSTRICTION AND PULMONARY GAS-EXCHANGE IN NORMAL MAN
    MELOT, C
    NAEIJE, R
    HALLEMANS, R
    LEJEUNE, P
    MOLS, P
    [J]. RESPIRATION PHYSIOLOGY, 1987, 68 (01): : 11 - 27
  • [3] LOCAL PULMONARY BLOOD-FLOW - CONTROL AND GAS-EXCHANGE
    SHEEHAN, DW
    FARHI, LE
    [J]. RESPIRATION PHYSIOLOGY, 1993, 94 (01): : 91 - 107
  • [4] INFLUENCE OF PULMONARY BLOOD-FLOW ON GAS-EXCHANGE IN PIGLETS
    ESCOURROU, P
    QI, X
    WEISS, M
    MAZMANIAN, GM
    GAULTIER, C
    HERVE, P
    [J]. JOURNAL OF APPLIED PHYSIOLOGY, 1993, 75 (06) : 2478 - 2483
  • [5] EFFECTS OF ALMITRINE ON HYPOXIC PULMONARY VASOCONSTRICTION AND PULMONARY GAS-EXCHANGE IN NORMAL MAN
    MELOT, C
    DECHAMPS, P
    HALLEMANS, R
    DECROLY, P
    MOLS, P
    [J]. BULLETIN EUROPEEN DE PHYSIOPATHOLOGIE RESPIRATOIRE-CLINICAL RESPIRATORY PHYSIOLOGY, 1986, 22 : S102 - S102
  • [6] DOES HYPOXIC VASOCONSTRICTION PLAY A PART IN DISTRIBUTION OF PULMONARY BLOOD-FLOW
    PREFAUT, C
    RUFF, F
    [J]. CLINICAL RESPIRATORY PHYSIOLOGY-BULLETIN EUROPEEN DE PHYSIOPATHOLOGIE RESPIRATOIRE, 1980, 16 (03): : 367 - 381
  • [7] Predicting The Influence Of Hypoxic Pulmonary Vasoconstriction On The Distribution Of Pulmonary Blood Flow
    Burrowes, K. S.
    Swan, A. J.
    Clark, A. R.
    Croft, Q. P. P.
    Dorrington, K. L.
    Robbins, P. A.
    Tawhai, M. H.
    [J]. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2011, 183
  • [8] Effects of hypoxic pulmonary vasoconstriction on pulmonary gas exchange
    Brimioulle, S
    Lejeune, P
    Naeije, R
    [J]. JOURNAL OF APPLIED PHYSIOLOGY, 1996, 81 (04) : 1535 - 1543
  • [9] REDUCED PULMONARY BLOOD-FLOW IMPROVES GAS-EXCHANGE IN NEWBORN PIGLETS
    REDDING, GJ
    GIBSON, R
    TWIGGS, G
    STANDAERT, TA
    TRUOG, WE
    [J]. AMERICAN REVIEW OF RESPIRATORY DISEASE, 1986, 133 (04): : A151 - A151
  • [10] EFFECT OF LOCAL PULMONARY BLOOD-FLOW CONTROL ON GAS-EXCHANGE - THEORY
    GRANT, BJB
    [J]. JOURNAL OF APPLIED PHYSIOLOGY, 1982, 53 (05) : 1100 - 1109
12345