ALPHA-D-GLUCOPYRANOSYL-PHENYLDIAZOMETHANE, A MECHANISM-BASED ALPHA-GLUCOSIDASE INHIBITOR

被引：8
|
作者：
DIETRICH, H [1 ]
SCHMIDT, RR [1 ]
机构：
[1] UNIV KONSTANZ,FAK CHEM,D-78434 CONSTANCE,GERMANY
来源：
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1994年 / 4卷 / 04期
关键词：
D O I：
10.1016/S0960-894X(01)80162-1
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
The title compound 8 was readily prepared from known alpha-benzyl-C-glucoside 2, its transformation into N-Nitroso-urethane derivative 5, and then treatment with base. 8 showed irreversible inhibition against alpha-glucosidase from yeast.
引用
收藏
页码：599 / 604
页数：6
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