EVOLUTION AND AGGREGULATES - ROLE OF THE POLYCOMB-GROUP GENES OF DROSOPHILA

被引：0
|
作者：
SANTAMARIA, P
机构：
来源：
COMPTES RENDUS DE L ACADEMIE DES SCIENCES SERIE III-SCIENCES DE LA VIE-LIFE SCIENCES | 1993年 / 316卷 / 10期
关键词：
AGGREGULATES; EVOLUTION; HOMEOTIC GENES; REGULATORY GENES;
D O I：
暂无
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
The Polycomb-group (Pc-G) genes of Drosophila melanogaster are responsible for fixation of the repressed state for other selector genes, mostly homeotic but not exclusively. Different arguments suggest that they work cooperatively by specific recognition and structural modification of their targets. Their pleiotropic mutant phenotypes are strikingly similar to morphological traits used to classify Dipteran groups. I propose that the products of Pc-G genes can form a combinatorial multimeric regulatory system (the Aggregulates of F. Jacob) and that stable variations in the composition of this system have played an important role in Dipteran evolution.
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页码：1200 / 1206
页数：7
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