DISSOCIATION BETWEEN PLASMA-CONCENTRATIONS OF THYROXINE AND INSULIN-LIKE GROWTH FACTOR-I

被引：4
|
作者：
DAUNCEY, MJ [1 ]
MOROVAT, A [1 ]
RUDD, BT [1 ]
SHAKESPEAR, RA [1 ]
机构：
[1] BIRMINGHAM & MIDLAND HOSP WOMEN,DEPT CLIN ENDOCRINOL,BIRMINGHAM B11 4HL,W MIDLANDS,ENGLAND
来源：
EXPERIMENTAL PHYSIOLOGY | 1990年 / 75卷 / 05期
关键词：
D O I：
10.1113/expphysiol.1990.sp003454
中图分类号：
Q4 [生理学];
学科分类号：
071003 ;
摘要：
The relation between plasma concentrations of thyroxine (T4) and insulin‐like growth factor‐I (IGF‐I) has been examined in young, growing pigs under controlled conditions of energy intake. Compared with euthyroid controls, plasma levels of IGF‐I were significantly elevated (P less than 0.005) both in hypothyroid animals on the same food intake and in hyperthyroid animals on double the food intake. There was however no increase in IGF‐I in a hyperthyroid group on the control level of intake. Contrary to previous reports in which energy intake was not controlled, it is concluded that there is no simple correlation between plasma concentrations of T4 and IGF‐I. © 1990 The Physiological Society
引用
收藏
页码：729 / 731
页数：3
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