ISOFORMS OF GLUCOSE-TRANSPORTER IN THE IRIS-CILIARY BODY

被引：0
|
作者：
TSUKAMOTO, H [1 ]
MISHIMA, HK [1 ]
KUROKAWA, T [1 ]
KIUCHI, Y [1 ]
SATO, E [1 ]
ISHIBASHI, S [1 ]
机构：
[1] HIROSHIMA UNIV,SCH MED,DEPT PHYSIOL CHEM,MINAMI KU,HIROSHIMA 734,JAPAN
来源：
JAPANESE JOURNAL OF OPHTHALMOLOGY | 1995年 / 39卷 / 03期
关键词：
CYTOCHALASIN B BINDING ASSAY; GLUCOSE TRANSPORTER; IRIS-CILIARY BODY; WESTERN BLOT ANALYSIS;
D O I：
暂无
中图分类号：
R77 [眼科学];
学科分类号：
100212 ;
摘要：
Isoforms of the facilitated glucose transporter (GLUT) were identified in the iris-ciliary body. Western blot analysis showed that GLUT1 and GLUT4 proteins were expressed in the rat iris-ciliary body. In addition, the content of GLUT proteins in the rabbit iris-ciliary body was estimated by specific [H-3]cytochalasin B binding assay. The content of GLUT proteins was found to be more abundant in the iris-ciliary body than in the cerebral cortex. The utilization of glucose in the iris-ciliary body and the transport of glucose into the aqueous humor are suggested to be mediated by GLUT1 and GLUT4 proteins.
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页码：242 / 247
页数：6
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