A model of the development of living organisms is presented which couples the geometry of the middle surface of a (closed) epithelial surface to a ''morphogen'', and the morphogen in turn is affected by the geometry of the surface in a closed system of two partial differential equations. A number of ''desiderata'' are set out for the identification of a suitable morphogen. Four parameters are involved in the model, which are assumed to be under genetic control. The morphogen is pictured as an adhesive molecule on the cell surface, and a suggestion is made for a particular molecular manifestation of this morphogen. A simple picture of gastrulation is presented as an example of the formalism.
机构:
Univ Leipzig, Math Inst, Augustuspl 10-11, D-04109 Leipzig, GermanyUniv Leipzig, Math Inst, Augustuspl 10-11, D-04109 Leipzig, Germany
Brinkschulte, Judith
Hill, C. Denson
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机构:
SUNY Stony Brook, Dept Math, Stony Brook, NY 11794 USAUniv Leipzig, Math Inst, Augustuspl 10-11, D-04109 Leipzig, Germany
Hill, C. Denson
Leiterer, Juergen
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机构:
Lumboldt Univ Berlin, Inst Math, Unter Linden 6, D-10099 Berlin, GermanyUniv Leipzig, Math Inst, Augustuspl 10-11, D-04109 Leipzig, Germany
Leiterer, Juergen
Nacinovich, Mauro
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机构:
II Univ Roma Tor Vergata, Dipartimeuto Matemat, Via Ric Sci, I-00133 Rome, ItalyUniv Leipzig, Math Inst, Augustuspl 10-11, D-04109 Leipzig, Germany
Nacinovich, Mauro
[J].
BOLLETTINO DELLA UNIONE MATEMATICA ITALIANA,
2020,
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: 71
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