ACUTE AND CHRONIC TOXICITY TESTING IN THE ASSESSMENT OF FOOD ADDITIVE SAFETY

被引：0

作者：

HATTAN, DG

机构：

来源：

ACS SYMPOSIUM SERIES | 1992年 / 484卷

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D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

This paper describes the history and present policy of the Food and Drug Administration regarding the use of the LD50 test procedure in support of the safety of food additives. Current issues affecting long-term testing such as the maximum tolerated dose and the survival of animals are discussed. The toxicological safety assessment of novel foods with low caloric density provides regulatory toxicologists with a special challenge.

引用

页码：99 / 104

页数：6

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