A biochemical model and results of numerical simulation of the propagation of electromechanical waves of deformation alone the small bowel are presented. The organ in modelled as a soft orthotropic cylindrical biological shell reinforced by orthogonally interwoven smooth muscle elements, embedded in a connective tissue network. The dynamic reaction starts as a response to the propagation of a depolarization wave along the smooth muscle layers. The muscle layers contract independently but in a coordinated way with the generation of active forces. The mechanical properties of the wall are assumed to be nonlinear. Deformations of the bioshell are finite. The governing system of equations is obtained and solved numerically. The finite-difference method of the second order accuracy over the time and space variables was used. The dynamics of strain distribution in the biological shell and shape changes are analysed.
机构:
Mayo Clin & Mayo Fdn, Gastroenterol Res Unit, Enter Neurosci Grp, Enter Neurosci Program, Rochester, MN 55905 USAMayo Clin & Mayo Fdn, Gastroenterol Res Unit, Enter Neurosci Grp, Enter Neurosci Program, Rochester, MN 55905 USA
Aros, SD
Camilleri, M
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机构:
Mayo Clin & Mayo Fdn, Gastroenterol Res Unit, Enter Neurosci Grp, Enter Neurosci Program, Rochester, MN 55905 USAMayo Clin & Mayo Fdn, Gastroenterol Res Unit, Enter Neurosci Grp, Enter Neurosci Program, Rochester, MN 55905 USA