EQUIPMENT FOR MULTIFUNCTIONAL USE IN HIGH-PERFORMANCE CAPILLARY ELECTROPHORESIS

Instrumental aspects of capillary electrophoresis are reported. The instrument discussed can operate in the ''open'' and ''closed'' modes. All kinds of capillaries and capillary diameters can be applied. With this apparatus it is possible to perform analysis in free solutions, such as zone electrophoresis, isotachophoresis and isoelectric focusing. Gel-filled columns can also be used and systems making use of micellar electrokinetic chromatography. Several examples of separations of mixtures of organic acids in the open and closed modes are given. A separation of DNA restriction digest in a gel-filled column in the open and closed modes is described. A rapid analysis in an open system of guanine from mites in house dust is reported.