SEQUENCE AND LOCALIZATION OF A NOVEL FK506-BINDING PROTEIN TO MOUSE CHROMOSOME-11

被引：9
|
作者：
SIMEK, SL
KOZAK, CA
WINTERSTEIN, D
HEGAMYER, G
COLBURN, NH
机构：
[1] NCI,FREDERICK CANC RES & DEV CTR,VIRAL CARCINOGENESIS LAB,FREDERICK,MD 21702
[2] NIAID,MOLEC MICROBIOL LAB,BETHESDA,MD 20892
来源：
GENOMICS | 1993年 / 18卷 / 02期
关键词：
D O I：
10.1006/geno.1993.1485
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
We have isolated a unique gene from a mouse JB6 epidermal cell cDNA expression library, termed FKBPRP, that codes for a protein having domains that share between 37 and 44% amino acid sequence identity and 60% similarity with members of the family of FK506-binding proteins. The FKBPRP protein has three repeats contained within its sequence that share between 48 and 58% identity to each other. We have localized the FKBPRP gene to mouse Chromosome 11, and crosses of different murine strains provided the gene order centromere-FKBPRP-Int-4-Pkca-Es-3. © 1993 Academic Press. All rights reserved.
引用
收藏
页码：407 / 409
页数：3
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