DELAYED-HYPERSENSITIVITY REACTION AFTER INFUSION OF NONIONIC INTRAVENOUS CONTRAST MATERIAL FOR AN EXCRETORY UROGRAM - A CASE-REPORT AND REVIEW OF THE LITERATURE

Delayed adverse reactions to ionic and nonionic intravenous contrast media have been reported previously. We report a case in which delayed hypersensitivity to iohexol, a nonionic intravenous contrast agent commonly used in excretory urography, resulted in a bi-phasic allergic response. This reaction consisted of a mild post-infusion episode of urticaria, which preceded and was clinically distinct from a moderately severe dermatological eruption. The episode of urticaria was self-limited. The dermatological reaction was treated successfully with antihistamine therapy.