THE ROLE OF C-MYC IN CELL-GROWTH

被引：371
|
作者：
EVAN, GI [1 ]
LITTLEWOOD, TD [1 ]
机构：
[1] IMPERIAL CANC RES FUND, LONDON WC2A 3PX, ENGLAND
来源：
CURRENT OPINION IN GENETICS & DEVELOPMENT | 1993年 / 3卷 / 01期
关键词：
D O I：
10.1016/S0959-437X(05)80339-9
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Recent experiments have established that the c-myc oncogene encodes a sequence-specific DNA-binding protein that interacts with a specific intracellular partner, Max, and probably manifests its effects through transcriptional modulation. In addition, the range of biological functions attributed to expression of c-myc has grown to include not only transformation and mitogenesis but also cell death.
引用
收藏
页码：44 / 49
页数：6
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