NEUROENDOCRINOLOGICAL APPROACH FOR EXAMINING THE MECHANISMS OF ACTION OF TOKI-SHAKUYAKU-SAN (TJ-23) ON THE ACTIVITY OF TYROSINE-HYDROXYLASE IN THE BRAIN

被引：3
|
作者：
TORIIZUKA, K
HAGINO, N
TERASAWA, K
机构：
[1] UNIV TEXAS,HLTH SCI CTR,DEPT CELLULAR & STRUCT BIOL,SAN ANTONIO,TX 78284
[2] TOYAMA MED & PHARMACEUT UNIV,DEPT JAPANESE ORIENTAL KAMPO MED,TOYAMA,TOYAMA 93001,JAPAN
来源：
PHYTOTHERAPY RESEARCH | 1993年 / 7卷
关键词：
KAMPO MEDICINES; BRAIN TYROSINE HYDROXYLASE; RATS;
D O I：
10.1002/ptr.2650070721
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Administration of the Kampo medicine, TJ-23, to ovariectomized rats resulted in decreased tyrosis hydroxylase (TH) activity in the dorsal hippocampus but an increased activity in the ventral tegmental area. A decrease of TH activity in the hypothalamus was not statistically significant. The effect of TJ-23 was compared to oestrogen in a similar group of rats and it was concluded that the standard drug and TJ-23 induced similar effects.
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页码：S70 / S72
页数：3
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