SYSTEMIC LUPUS-ERYTHEMATOSUS

被引：11
|
作者：
PISETSKY, DS [1 ]
机构：
[1] VET ADM MED CTR,DURHAM,NC
来源：
CURRENT OPINION IN IMMUNOLOGY | 1991年 / 3卷 / 06期
关键词：
D O I：
10.1016/S0952-7915(05)80014-7
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Systemic lupus erythematosus is a prototypic autoimmune disease characterized by antinuclear antibody production. In recent investigations, the contributions of various polymorphic immune response gene systems to disease pathogenesis have been analyzed. Unique cellular and molecular studies have also established the role of 'autoantigen drive' in autoantibody induction and its relationship to polyclonal B-cell activation.
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页码：917 / 923
页数：7
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