PEZ - A NOVEL HUMAN CDNA-ENCODING PROTEIN-TYROSINE PHOSPHATASE-LIKE AND EZRIN-LIKE DOMAINS

被引：51
|
作者：
SMITH, AL
MITCHELL, PJ
SHIPLEY, J
GUSTERSON, BA
ROGERS, MV
CROMPTON, MR
机构：
[1] INST CANC RES,CELL BIOL & EXPTL PATHOL SECT,SUTTON SM2 5NG,SURREY,ENGLAND
[2] WELLCOME RES LABS,DIV BIOL,MOLEC PHARMACOL SECT,BECKENHAM BR3 3BS,KENT,ENGLAND
来源：
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1995年 / 209卷 / 03期
关键词：
D O I：
10.1006/bbrc.1995.1591
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
We have isolated cDNAs from normal human breast tissue and breast tumour cells that encode a protein (pet) with features of a novel non-receptor tyrosine phosphatase possessing N-terminal sequence homology to the ezrin-band 4.1-merlin-radixin protein family. Northern blot analysis indicates that pet is expressed in a variety of human tissues including kidney, skeletal muscle, lung and placenta. Fluorescence in situ hybridization has mapped pet to chromosome 1 region q32.2-41. Sequence identity to a characterized polymorphic marker confirms this localization. (C) 1995 Academic Press, Inc.
引用
下载
收藏
页码：959 / 965
页数：7
相关论文
共 50 条
  • [1] Substrate Binding in Protein-tyrosine Phosphatase-like Inositol Polyphosphatases
    Gruninger, Robert J.
    Dobing, Selina
    Smith, Adam D.
    Bruder, Lisza M.
    Selinger, L. Brent
    Wieden, Hans-Joachim
    Mosimann, Steven C.
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2012, 287 (13) : 9722 - 9730
  • [2] Isolation of Protein-Tyrosine Phosphatase-like Member-a Variant from Cementum
    Valdes De Hoyos, A.
    Hoz-Rodriguez, L.
    Arzate, H.
    Narayanan, A. S.
    JOURNAL OF DENTAL RESEARCH, 2012, 91 (02) : 203 - 209
  • [3] SRC KINASE ASSOCIATES WITH A MEMBER OF A DISTINCT SUBFAMILY OF PROTEIN-TYROSINE PHOSPHATASES CONTAINING AN EZRIN-LIKE DOMAIN
    MOLLER, NPH
    MOLLER, KB
    LAMMERS, R
    KHARITONENKOV, A
    SURES, I
    ULLRICH, A
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1994, 91 (16) : 7477 - 7481
  • [4] CLONING AND CHARACTERIZATION OF A HUMAN CDNA-ENCODING A NOVEL PUTATIVE CYTOPLASMIC PROTEIN-TYROSINE-PHOSPHATASE
    TAKEKAWA, M
    ITOH, F
    HINODA, Y
    ARIMURA, Y
    TOYOTA, M
    SEKIYA, M
    ADACHI, M
    IMAI, K
    YACHI, A
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1992, 189 (02) : 1223 - 1230
  • [5] Three protein-tyrosine phosphatase-like proteins are required for resistance to a lipid hydroperoxide.
    Alic, N
    Higgins, VJ
    Breitenbach, M
    Dawes, IW
    YEAST, 2003, 20 : S189 - S189
  • [6] Protein tyrosine phosphatase-like proteins: Link with IDDM
    Pietropaolo, M
    Hutton, JC
    Eisenbarth, GS
    DIABETES CARE, 1997, 20 (02) : 208 - 214
  • [7] ACID-PHOSPHATASE PURIFIED FROM MYCOPLASMA-FERMENTANS HAS PROTEIN-TYROSINE PHOSPHATASE-LIKE ACTIVITY
    SHIBATA, KI
    NODA, M
    SAWA, Y
    WATANABE, T
    INFECTION AND IMMUNITY, 1994, 62 (01) : 313 - 315
  • [8] Characterization of STYX: A novel phosphatase-like protein
    Wishart, MJ
    Wiliams, JA
    Dixon, JE
    FASEB JOURNAL, 1997, 11 (09): : A1182 - A1182
  • [9] ISOLATION OF A CDNA CLONE ENCODING A HUMAN PROTEIN-TYROSINE PHOSPHATASE WITH HOMOLOGY TO THE CYTOSKELETAL-ASSOCIATED PROTEINS BAND-4.1, EZRIN, AND TALIN
    YANG, Q
    TONKS, NK
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1991, 88 (14) : 5949 - 5953
  • [10] CLONING AND EXPRESSION OF PROTEIN-TYROSINE PHOSPHATASE-LIKE PROTEIN-DERIVED FROM A RAT PHEOCHROMOCYTOMA CELL-LINE
    KAMBAYASHI, Y
    TAKAHASHI, K
    BARDHAN, S
    INAGAMI, T
    BIOCHEMICAL JOURNAL, 1995, 306 : 331 - 335
12345