INFANTILE STIMULATION AND THE ROLE OF THE BENZODIAZEPINE RECEPTOR SYSTEM IN ADULT ACQUISITION OF 2-WAY AVOIDANCE-BEHAVIOR

被引：19

作者：

ESCORIHUELA, RM ^{[1
]}

FERNANDEZTERUEL, A ^{[1
]}

NUNEZ, FJ ^{[1
]}

ZAPATA, A ^{[1
]}

TOBENA, A ^{[1
]}

机构：

[1] AUTONOMOUS UNIV BARCELONA,SCH MED,DEPT PSYCHIAT,E-08193 BARCELONA,SPAIN

来源：

PSYCHOPHARMACOLOGY | 1992年 / 106卷 / 02期

关键词：

POSTNATAL EXPERIENCE; HANDLING; RO; 15-1788; COPING BEHAVIOR; EMOTIONAL REACTIVITY; RAT;

D O I：

10.1007/BF02801985

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The present study shows that postnatal "consistent" handling (CH) of rats had long-lasting improving effects on coping with an stressful task (i.e. two-way active avoidance), and that such effects were partially prevented by acute Ro 15-1788 (antagonist of benzodiazepine receptor-BZR; 5 mg/kg) administration. Long-lasting detrimental effects in the same task were also observed in rats which received postnatal "inconsistent" handling (INCH), effects that were slightly increased by acute Ro 15-1788 treatment. Finally, Ro 15-1788 tended to increase avoidance acquisition in non-handled (NH) animals. The observed effects of Ro 15-1788 could be partially attributed to a differential modulation of the process of avoidance acquisition depending on postnatal treatments producing different levels of emotionality.

引用

页码：282 / 284

页数：3

共 50 条

[1] EFFECTS OF EARLY MALNUTRITION ON ONE-WAY AND 2-WAY AVOIDANCE-BEHAVIOR
MORRIS, CJ
[J]. PHYSIOLOGICAL PSYCHOLOGY, 1974, 2 (02): : 148 - 150
[2] FACILITATORY EFFECT OF PRENATAL X-IRRADIATION ON 2-WAY AVOIDANCE-BEHAVIOR IN RATS
TAMAKI, Y
SHOJI, R
TAKEUCHI, IK
MURAKAMI, U
[J]. JAPANESE PSYCHOLOGICAL RESEARCH, 1976, 18 (03) : 142 - 146
[3] AVOIDANCE-BEHAVIOR IN ADULT 2ND LANGUAGE-ACQUISITION
KLEINMANN, HH
[J]. LANGUAGE LEARNING, 1977, 27 (01) : 93 - 107
[4] 2-WAY AVOIDANCE-BEHAVIOR OF THE ROMAN RAT STRAINS FOLLOWING BRAIN-LESIONS
GUENAIRE, C
DELACOUR, J
[J]. PHYSIOLOGY & BEHAVIOR, 1983, 31 (02) : 159 - 166
[5] GENERALITY AND FACILITY OF 2-WAY AVOIDANCE-BEHAVIOR IN THE PHARMACOLOGICAL TESTING OF SELECTIVELY-BRED RATS
FUCHS, A
HARTING, J
DRISCOLL, P
[J]. EXPERIENTIA, 1980, 36 (06): : 707 - 707
[6] THE EFFECTS OF PRENATAL CHLORDIAZEPOXIDE ADMINISTRATION ON AVOIDANCE-BEHAVIOR AND BENZODIAZEPINE RECEPTOR DENSITY IN ADULT ALBINO-RATS
AVNIMELECHGIGUS, N
FELDON, J
TANNE, Z
GAVISH, M
[J]. EUROPEAN JOURNAL OF PHARMACOLOGY, 1986, 129 (1-2) : 185 - 188
[7] CENTRAL CHOLINERGIC BLOCKADE AND 2-WAY AVOIDANCE ACQUISITION - ROLE OF RESPONSE DISINHIBITION
BIGNAMI, G
AMORICO, L
FRONTALI, M
ROSIC, N
[J]. PHYSIOLOGY & BEHAVIOR, 1971, 7 (04) : 461 - &
[8] MATERNAL-BEHAVIOR IN 2 RAT LINES SELECTED FOR DIFFERENCES IN THE ACQUISITION OF 2-WAY AVOIDANCE
DRISCOLL, P
FUMM, H
BATTIG, K
[J]. EXPERIENTIA, 1979, 35 (06): : 786 - 788
[9] EPILEPTIFORM LESIONS IN RAT HIPPOCAMPUS AND ACQUISITION OF 2-WAY AVOIDANCE
WOODRUFF, ML
FISH, BS
ALDERMAN, AO
[J]. PHYSIOLOGY & BEHAVIOR, 1977, 19 (03) : 401 - 410
[10] INFLUENCE OF ENUCLEATION UPON 2-WAY AVOIDANCE-BEHAVIOR OF RATS, HAMSTERS, CHINCHILLAS AND BALB-CJ MICE
DYER, RS
HAMMOND, MA
WELDON, DA
BOOKER, TC
[J]. PHYSIOLOGY & BEHAVIOR, 1975, 14 (02) : 211 - 216

← 1 2 3 4 5 →