SAFETY AND EFFICACY OF A BULK LAXATIVE CONTAINING SENNA VERSUS LACTULOSE IN THE TREATMENT OF CHRONIC CONSTIPATION IN GERIATRIC-PATIENTS

被引：1
|
作者：
KINNUNEN, O
WINBLAD, I
KOISTINEN, P
SALOKANNEL, J
机构：
[1] KONTINKANGAS HOSP OULU,OULU,FINLAND
[2] UNIV OULU,DEPT PUBL HLTH SCI & GEN PRACTICE,SF-90100 OULU 10,FINLAND
来源：
PHARMACOLOGY | 1993年 / 47卷
关键词：
SENNA; LACTULOSE; BULK LAXATIVES; CLINICAL USE; GERIATRICS;
D O I：
暂无
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Thirty geriatric long-stay patients aged 65-94 years (mean 81.8) participated in the trial the aim of which was to examine bulk laxative plus senna (Agiolax(R)) in the treatment of chronic constipation using lactulose (Levolac(R)) as a reference medicine. Bulk laxative plus senna (daily dosis 14.8 g) produced more frequent (p < 0.05) bowel habits (4.5 vs. 2.2-1.9/week) than lactulose (daily dosis 20.1 g). Both laxatives proved to be safe to use. Our study indicated bulk laxative plus senna to be more efficient in treating constipation in geriatric long-stay patients.
引用
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页码：253 / 255
页数：3
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