High-dose treatment of more than three months' duration reduces bone mass, regardless of the patient's age, sex, or race, Because bone loss is most severe during the first six to 12 months of treatment, prophylaxis to preserve bone-with calcium, vitamin D, a bisphosphonate, and exercise-should begin as soon as the clinical situation permits rather than after the disease has been brought under control.
机构:
Teikyo Univ, Sch Med, Dept Internal Med, Itabashi Ku, Tokyo 1738605, JapanTeikyo Univ, Sch Med, Dept Internal Med, Itabashi Ku, Tokyo 1738605, Japan
Tamura, Y
Okinaga, H
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机构:Teikyo Univ, Sch Med, Dept Internal Med, Itabashi Ku, Tokyo 1738605, Japan
Okinaga, H
Takami, H
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机构:Teikyo Univ, Sch Med, Dept Internal Med, Itabashi Ku, Tokyo 1738605, Japan