VIRULENCE-ASSOCIATED PLASMIDS IN RHODOCOCCUS-EQUI

被引：106

作者：

TAKAI, S ^{[1
]}

WATANABE, Y ^{[1
]}

IKEDA, T ^{[1
]}

OZAWA, T ^{[1
]}

MATSUKURA, S ^{[1
]}

TAMADA, Y ^{[1
]}

TSUBAKI, S ^{[1
]}

SEKIZAKI, T ^{[1
]}

机构：

[1] NATL INST ANIM HLTH,TSUKUBA,IBARAKI 305,JAPAN

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 1993年 / 31卷 / 07期

关键词：

D O I：

10.1128/JCM.31.7.1726-1729.1993

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Twenty-three strains of Rhodococcus equi from independent clinical cases were analyzed for the presence of virulence plasmid DNA. Of the clinical isolates, 19 contained an 85-kb plasmid and the remaining 4 contained a 90-kb plasmid. All of the isolates expressed 15- to 17-kDa antigens and were virulent in mice. Restriction enzyme and Southern blot analyses showed large regions of DNA homology between the 85- and 90-kb virulence plasmids. It was concluded tentatively that there are at least two virulence plasmids in R. equi and that they have a common origin.

引用

页码：1726 / 1729

页数：4

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